The Biotechnology Network involves a number of distributed technical facilities accessible to all scientists in the State of Oklahoma having need in their research or private sector activities. The facilities described below provide training in the application of new technologies in addition to direct access to facility instrumentation or services.
The Recombinant DNA / Protein Facility in the Department of Biochemistry and Molecular Biology, Oklahoma State University - Facilities supporting both DNA and Protein Biochemistry are available. These include: DNA Sequencing, Oligonucleotide Synthesis, Protein Sequencing, and Peptide Synthesis which are all offered as a service. The Facility also provides training and workshops in Recombinant DNA Techniques, Polymerase Chain Reaction and its Applications, Protein Purification Strategies, and DNA Library Construction. Contact: Dr. John Cushman or Dr. Steve White, Department of Biochemistry and Molecular Biology, Oklahoma State University, Stillwater, OK 74078. Phone 405-744-6189; FAX 405-744-7799;
Web Site http://bmb-fs1.biochem.okstate.edu/Core/COREHomepage.html
The Hybridoma Facility in the Department of Entomology and Plant Pathology, Oklahoma State University - The hybridoma facility provides services and training in monoclonal antibody and polyclonal antibody production, including preparation of antigens used in the immunization process. Contact: Dr. Russ Wright, Department of Entomology and Plant Pathology, Oklahoma State University, Stillwater, OK 74078.
The Plant Transformation Facility in the Department of Plant and Soil Sciences, Oklahoma State University - The plant transformation facility offers services and training in transformation of both monocot and dicot plant species. Assistance is provided in initial stages of the transformation processes, including direct (Biolistics or electroporation) and bacterial (Agrobacterium) methods of DNA transmission into desired plant species. Contact: Dr. Arron Guenzi, Department of Plant and Soil Sciences, Oklahoma State University, Stillwater, OK 74078-6028. Phone 405-744-5532,
Web Site http://www.agr.okstate.edu/ptf/
The Oklahoma University Advanced Center for Genome Technology in the Department of Chemistry, University of Oklahoma - The major goal of this facility is to provide state-of-the-art DNA Sequencing and computing facility which supports large scale genomic DNA sequencing projects. This facility currently is involved in determining the sequence of human chromosome 22 and syntenic regions of the mouse genome, and determining the complete nucleotide sequence of two bacterial genomes, Neisseria gonorrhoeae and Streptococcus pyogenes. The facility also provides training for visiting, collaborating scientists and has established a centrally located computing facility that provides Oklahoma scientists with internet access to a wide range of genetic, molecular biological and biochemical related computer programs and databases. Contact: Dr. Bruce Roe, Department of Chemistry and Biochemistry, University of Oklahoma, Norman, OK 73019. Phone: 405-325-4912. FAX: 405-325-7762.
Web site: http://www.genome.ou.edu/
The Ultrastructural Studies Center in the Department of Botany and Microbiology at the University of Oklahoma - The facility provides training and services to individuals interested in immunological and molecular probes to study cell ultrastructure and to localize cellular constituents using electron microscopy. The facility is operated in conjunction with the Noble Electron Microscopy Laboratory at the University of Oklahoma. Contact: Dr. Karel Schubert, Department of Botany and Microbiology, 770 Van Vlet Oval, University of Oklahoma, Norman, OK 73019. Phone: 405-325-6982; FAX 405-325-4053.
The Laser Mass Spectrometer Facility in the Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center - The laser mass spectrometer facility provides this state-of-the-art technology for analysis of biological materials to investigators in Oklahoma. Contact: Dr. Jay Hanas, Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73190. Phone 405-271-2227 FAX 405-271-3092.
The Comparative Sequence Facility in the Department of Biological Sciences, University of Tulsa - The comparative sequence facility provides small scale automated DNA sequencing and has expertise in the specific analysis of DNA sequences for evolutionary comparisons. Contact: Dr. Glen Collier, Department of Biological Sciences, University of Tulsa, Tulsa, OK 74104. Phone 918-631-2758 FAX 918-631-2762.
The Transgenic Mouse Facility at the Oklahoma Medical Research Foundation - The Oklahoma Medical Research Foundation houses a transgenic mouse facility and is accessible to investigators within the State of Oklahoma. Funds are available through the EPSCoR Biotechnology Network to subsidize and stimulate use of the facility by non-OMRF investigators. Contact: Dr. Nancy Nadon, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma 26901.
The Oklahoma Statewide-Shared Nuclear Magnetic Resonance Facility in the Chemistry Department, Oklahoma State University - A State-Wide NMR Facility supported through a number of federal, private, and university resources is available to investigators in the State of Oklahoma. The facility will house both 600 MHz and 400 MHz nuclear magnetic resonance spectrometers with state-of-the-art instrumentation for a variety of biological applications. The NMR facilities will be linked via the internet to research centers at each of the major universities in Oklahoma. The 400 MHz instrument should be accessible Fall 1996 and the 600 MHz instrument will be installed early 1997. Contact: Dr. Warren Ford, Department of Chemistry, Oklahoma State University, Stillwater, OK 74078. Phone 405-744-5946 FAX 405-744-6007.
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